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Effects of Sublethal Doses of Cadmium on Plasma Thyroid Hormone Levels in Yellowfin Seabream (Acanthopagrus latus)
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Ali Vaboonian   , Abdolali Movahedinia |
| , amovahedinia@yahoo.com |
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Abstract: (10523 Views) |
| Cadmium is a heavy metal that is known as a pollutant in aquatic environments. This heavy metal may
cause destroying effects via affecting on fish endocrine glands and metabolism. Thyroid hormones have the
important role in growth, development and reproduction system in fish. The aim of the current study was the
assessment of Cadmium effects on thyroid function in male Yellowfin Seabream, Acanthopagrus latus. Fish
specimens were exposed to different Cadmium concentrations (1, 3, 6, 9 and 12 mg/liter) those were selected
according to the toxicity test, for 2 weeks. Blood samplings were conducted at 7 and 14 days after the test was
started. Plasma levels of thyroid hormones (triiodothyronine and tetraiodothyronine) were assayed using
Radioimmunoassay method. Plasma T3 levels and T3/T4 ratios had significant and indirect relation with
Cadmium concentrations whereas T4 showed direct relation and increased significantly after Cadmium
exposure. These results demonstrated the negative effects of Cadmium on thyroid hormones homeostasis via
inhibiting the 5'-monoiodinase and T4 to T3 conversion. |
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| Keywords: Heavy metal, Endocrine system, Thyroxin, Triiodothyronine, Biomarker. |
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Full-Text [PDF 144 kb]
(2195 Downloads)
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Type of Study: Research/ Original/ Regular Article |
Received: 2014/12/28 | Revised: 2015/02/28 | Accepted: 2014/12/28 | ePublished: 2014/12/28
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