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:: Volume 4, Issue 16 (2014) ::
2014, 4(16): 23-32 Back to browse issues page
Use of Thyroid Hormones and Micronucleus as Potential Early Biomarkers in Yellowfin Seabream (Acanthopagrus latus) Exposed to Bisphenol A
Ahmad Negintaji , Bita Archangi , Abdolali Movahedinia , Alireza Safahieh , Gholamreza Eskandari
Khorramshahr University of Marine Sciences and Technology , bita.archangi@gmail.com
Abstract:   (11820 Views)
Bisphenol A (BPA) is an endocrine disruptor (ED) that is abundant in marine environments because of its extensive use in manufacturing polycarbonate plastics and epoxy resins. In the present study, effects of BPA on thyroid hormones and blood cells were investigated to detect endocrine and cytogenetic damages in yellowfin seabream inhabited in selected sites in Musa Creek. The results indicated significant reduction in plasma triiodothyronine and high level of plasma thyroxine in treated fishes in comparison to the control groups and in dose dependent manner. In addition, using Micronucleus test (MN) showed induction of micronucleus in exposed fish samples. Therefore, the results of this project indicated the potential effects of (BPA) causing endocrine disruption and cytogenetic damages. Hence, monitoring thyroid hormones and undertaking MN test could be useful to evaluate the potential damage occurred in the fish samples either in controlled or natural marine environments.
Keywords: Thyroid hormones, Bisphenol A, Xenobiotic, Intraperitoneal injection, Yellowfin seabream (Acanthopagrus latus).
Full-Text [PDF 149 kb]   (2565 Downloads)    
Type of Study: Research/ Original/ Regular Article |
Received: 2014/03/23 | Revised: 2019/07/21 | Accepted: 2014/03/23 | ePublished: 2014/03/23


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Negintaji A, Archangi B, Movahedinia A, Safahieh A, Eskandari G. Use of Thyroid Hormones and Micronucleus as Potential Early Biomarkers in Yellowfin Seabream (Acanthopagrus latus) Exposed to Bisphenol A. Journal of Oceanography 2014; 4 (16) :23-32
URL: http://joc.inio.ac.ir/article-1-464-en.html


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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 4, Issue 16 (2014) Back to browse issues page
نشریه علمی پژوهشی اقیانوس شناسی Journal of Oceanography
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