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A review of Holothoria :properties and applications of sea cucumber bioactive substances
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Mohaddeseh Larypoor   , Ghazaleh Fotouhi |
| Islamic Azad university , ghazaleh.fotouhi@yahoo.com |
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Abstract: (40 Views) |
Background and Objectives: In recent years, extensive studies have been conducted to investigate the biological activities, nutritional value and important health benefits of marine bioactive materials. The present study is designed to review bioactive substances in sea cucumbers with emphasis on bioactive substances in Holothuria.
Methods: The survey has been conducted on Scopus and PubMed since 2005. Duplicate articles have been removed. The following keywords were used to investigate cellular toxicity and bioactive, antibacterial effects: holoturia, bioactive, antibacterial, and cytotoxic (Tsujimoto Yet al, 2017).
Findings: The bioactive effects of sea cucumbers, especially Holothuria species, represent a wide range of therapeutic applications. These include anti-inflammatory, anti-cancer, antibiotic, restorative, and many others.
Conclusion: The bioactive compounds in sea cucumber extract further clarify their relevance to their role in clinical settings and the discovery of bioactive peptides that will eventually lead to drug discovery. Future research in this area should also focus on optimizing extraction processes so that the precise function of these compounds is pharmacologically significant. The effect of extracts from some Holoturia species demonstrates natural inhibition of pathogenic bacteria, which could lead to the development of new antibiotic agents over time, given the growing global problem of antibiotic resistance.
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| Keywords: Bioactive substances, Holothoria, anti-bacterial |
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Type of Study: Review Article |
Subject:
Fisheries and Aquaculture
Received: 2025/01/31 | Revised: 2025/03/11 | Accepted: 2025/03/10
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