[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 8, Issue 32 (winter 2018) ::
joc 2018, 8(32): 1-8 Back to browse issues page
Change of Thyroid Hormone Levels in Mesopotamichthys sharpeyi Exposed to Sub Lethal Concentrations of Cadmium
Alireza Safahieh , Razieh Nasrolahzadeh * , Ahmad Negintaji
Abstract:   (722 Views)
Pollution of the aquatic ecosystems by heavy metals is posing serious threats to the survival of aquatic organisms including fish. Cadmium is a metal which is accumulated in high concentrations by a range of living organisms and which has unknown biological function. It enters aquatic environments especially via industrial wastes. Thyroid hormones have important roles in growth, development, metamorphosis, osmoregulation and reproduction in fishes. In the present study, the 96 hours LC50 of Cadmium on Binnei (Mesopotamichthys sharpeyi) was determined as 37.56 mg/l. The plasma thyroid hormones of Binnei through different sub lethal concentration of cadmium (1, 3, 6, 9 and 12 ppm) were assayed in order to determine the endocrine response of innei. Fish were exposed to different concentrations of cadmium as an endocrine disrupter during 2 weeks. Plasma thyroxine (T4) and triiodothyronine (T3) concentrations were determined using Radioimmunoassay method. In opposite manner, Plasma T3 was significantly decreased at days 7 and 14 by all doses of cadmium. Plasma T4 in treated fishes was increased in comparison to the control group in dose dependent manner. In conclusion, results of the current study indicated that the encounter of Binnei fish with Cadmium led to thyroid disruption of the fish which may  have treated for growth and fish health. 
Keywords: Cadmium, Biomarker, Thyroxin, Triiodothyronine, Mesopotamichthys sharpeyi.
Full-Text [PDF 116 kb]   (227 Downloads)    
Type of Study: Research |
References
1. Adams, B.A.; Cyr, D.G.; Eales, J.G., 2000. Thyroid hormone deiodination in tissues of American plaice, Hippoglossoides platessoides: characterization and short-term responses to polychlorinated biphenyls (PCBs) 77 and 126. Comparative Biochemistry and Physiology - Part C: Toxicology and Pharmacology, 127: 367-378.#
2. Agency for Toxic Substances and Disease Registry., 2007. Interaction profile for chlorpyrifos, lead, mercury, and methylmercury. Atlanta, GA: Agency for Toxic Substances and Disease Registry. http://www.atsdr. cdc.gov/interactionprofiles/IP-11/ip11.pdf. June 14, 2007.#
3. Becker, K.L., 2001. Principles and practice of endocrinology and metabolism. Lippincott Williams and Wilkins. 2477P.#
4. Brown, S.B.; Adams, B.A.; Cyr, D.G.; Eales, J.G., 2004. Contaminant effects on the teleost fish thyroid. Environmental Toxicology and Chemistry, 23: 1680-1701.#
5. Blanton, M.L.; Specker, J.L., 2007. The hypothalamic–pituitary–thyroid (HPT) axis in fish and its role in fish development and reproduction. Critical Reviews in Toxicology, 37: 97-115.#
6. Cizdziel, J.; Hinners, T.; Cross, C.; Pollard, J., 2003. Distribution of mercury in the tissues of five species of fresh water fish from Lake Mead, USA. Journal of Environmental Monitoring, 5: 802-807.#
7. Deane, E.E.; Li, J.; Woo, N.Y.S., 2001. Hormonal status and phagocytic activity in sea bream infected with vibriosis. Comparative Biochemistry and Physiology, 129: 687-693.#
8. Devlin, E.W., 2006. Acute toxicity, uptake and histopathology of aqueous methyl mercury to fathead minnow embryos. Ecotoxicology and Environmental Safety, 15: 97–110.#
9. Di Giulio, R.T.; Hinton, D.E., 2008. The Toxicology of Fishes. New York: Taylor & Francis, 1101P.#
10. Eales, J.G.; Brown, S.B., 2005. Thyroid hormones. In Biochemistry and molecular biology of fishes. Environmental Toxicology, 6: 397-412.#
11. Evans, G.O., 2009. Animal Hematotoxicology. CRC Press, 204P.#
12. Funes, V.; Asensio, E.; Ponce, M.; Infante, C.; Canavate, J.P.; Manchado, M., 2006. Insulin-like growth factors I and II in sole Solea senegalensis: cDNA cloning and quantitation of gene expression in tissues and during larval development. General and Comparative Endocrinology, 149: 166-172.#
13. Fort, D.J.; Degitz, S.; Tietge, J.; Touart, L.W., 2007. The hypothalamic–pituitary–thyroid (HPT) axis in frogs and its role in frog development and reproduction. Critical Reviews in Toxicology, 37: 117-161.#
14. Frias-Espericueta‚ M.G.; Castro-Longoria‚ R.; Barrón-Gallardo‚ G.J.; Osuna-López‚ J.I.; Abad-Rosales‚ S.M.; Páez-Osuna‚ F.; Voltolina‚ D., 2008. Histological changes and survival of Litopenaeus vannamei juveniles with different copper concentrations. Aquaculture, 278: 97-100.#
15. Goodwin, G.M., 2003. Evidence-based guidelines for treating bipolar disorder: recommendations from the British Association for Psychopharmacology. Journal of Psychopharmacology, 17: 149-173.#
16. Gilbertson, M.; Carpenter, D.O., 2004. An ecosystem approach to the health effects of mercury in the Great Lakes basin ecosystem. Environmental Research, 95: 240-246.#
17. Jugan, M.L.; Levi, Y.; Blondeau, J.P., 2010. Endocrine disruptors and thyroid hormone physiology. Biochemical Pharmacology, 79: 939-947.#
18. Labonne, M.; Othman, D.B.; Luck, J.M., 2001. Lead isotopes in muscels as tracers of metal sources and water movements in a Lagoon (Thau Basin, S. France). Chemical Geology, 181: 181-191.#
19. Lawrence, A.; Hemingway, K., 2003. Effects of pollution on fish, molecular effects and population responses. Blackwell Science Ltd, 362. #
20. Li, W.; Zha, J.M.; Li, Z.L.; Yang, L.H.; Wang, Z.J., 2009. Effects of exposure to acetochlor on the expression of thyroid hormone related genes in larval and adult rare minnow (Gobiocypris rarus). Aquatic Toxicology, 94: 87-93.#
21. Li, Z.H.; Chen, L.; Wu, Y.H.; Li, P.; Li, Y.F.; Ni, Z.H., 2014. Effects of waterborne cadmium on thyroid hormone levels and related gene expression in Chinese rare minnow larvae. Comparative Biochemistry and Physiology, Part C 161: 53-57.#
22. Martin-Diaz, M.L.; Villena-Lincoln, A.; Bamber, S.; Blasco, J.; DelValls, T.A., 2005. An integrated approach using bioaccumulation and biomarker measurements in female shore crab, Carcinus maenas. Chemospher, 58: 615-626.#
23. Mommsen, T.P.; Moon, T.W., 2005. Environmental toxicology-biochemistry and molecular biology of fishes. Elsevier Science Ltd, 577P.#
24. Nielsen, J.B.; Hultman, P., 2002. Mercury-induced autoimmunity in mice. Environmental Health Perspectives, 110: 877-881.#
25. Okimoto, D.; Tagawa, M.; Koide, Y.; Grau, E.; Hirano, T., 1991. Effects of various adenohypophysial hormones of chum salmon on thyroxine release in vitro in the medaka, Oryzias latipes. Zoological Science, 8: 567-573.#
26. Pratima, G.; Chaurasia, S.S.; Anand, K.; Maiti, P.K.; Gupta, P.; Kar, A., 1997. Influence of cadmium on thyroid hormone concentrations and lipid peroxidation in a fresh water fish, Clarias batrachus. Fresenius Environmental Bulletin, 6: 355-358.#
27. Ricard, A.C.; Daniel, C.; Anderson, P.; Hontela, A., 1998. Effects of subchronic exposure to cadmium chloride on endocrine and metabolic functions in Rainbow Trout Oncorhynchus mykiss. Environmental Contamination Toxicology, 34: 377-381.#
28. Risso-de Faverney, C.; Devaux, A.; Lafaurie, M.; Girard, J.P.; Bailly, B.; Rahmani, R., 2001. Cadmium induces apoptosis and genotoxicity in rainbow trout hepatocytes through generation of reactive oxygen species. Aquatic Toxicology, 53: 65-76.#
29. Snyder, E.M.; Snyder, S.A.; Kelly, K.L.; Gross, T.S.; Villeneuve, D.L.; Fitzgerald, S.D.; Villalobos, S.A.; Giesy, J.P., 2004. Reproductive responses of common carp (Cyprinus carpio) exposed in cages to influent of the Las Vegas Wash in Lake Mead, Nevada, from late winter to early spring. Environmental Science and Technology, 38: 6385-6395.#
30. Sutton, D.J.; Tchounwou, P.B., 2006. Mercury-induced externalization of phosphatidylserine and caspase 3 activation in human liver carcinoma (HepG2) cells. International Journal of Environmental Research and Public Health, 3(1): 38-42.#
31. Thangavel, P.; Sumathiral, K.; Karthikeyan, S.; Ramaswamy, M., 2005. Endocrine response of the freshwater teleost, Sarotherodon mossambicus (Peters) to dimecron exposure. Chemosphere, 61: 1083-92.#
32. Van der Oost, R.; Beyer, J.; Vermeulen, N.P.E., 2003. Fish bioaccumulation and biomarkers in environmental risk assessment: a review. Environmental Toxicology and Pharmacology, 13: 57-149.#
33. Wang, Q.W.; Liang, K.; Liu, J.F.; Yang, L.H.; Guo, Y.Y.; Liu, C.S.; Zhou, B.S., 2013. Exposure of zebrafish embryos/larvae to TDCPP alters concentrations of thyroid hormones and transcriptions of genes involved in the hypothalamic-pituitary-thyroid axis. Aquatic Toxicology, 126: 207-213.#
35. محمدیان، ت.؛ سیلاوی، م.؛ حسینی ا.ر.؛ حیدری، ب.؛ مصباح، م.؛ بیتا، س.، 1393. زی فن نوین تکثیر مصنوعی ماهی بنی در ایران. شیلات، مجله منابع طبیعی ایران، 67 (3): 412-405.#
36. نگین تاجی، الف.؛ ارچنگی، ب.؛ موحدی نیا، ع.؛ صفاهیه، ع.؛ اسکندری، غ.، 1392. استفاده از هورمون‌های تیروئیدی و میکرونوکلئوس به عنوان بیومارکرهای اولیه در مواجهه با ماده آلاینده بیس فنل آ در ماهی شانک زردباله (Acanthopagrus latus). نشریه اقیانوس شناسی، 16: 32-23.#
37. وابونیان، ع.؛ موحدی نیا، ع.، 1393. تاثیر غلظت‌های تحت کشنده کادمیوم بر هورمون‌های تیروئیدی ماهی شانک زردباله (Acanthopagrus latus). نشریه اقیانوس شناسی، 19: 34-27.#
38. Adams, B.A.; Cyr, D.G.; Eales, J.G., 2000. Thyroid hormone deiodination in tissues of American plaice, Hippoglossoides platessoides: characterization and short-term responses to polychlorinated biphenyls (PCBs) 77 and 126. Comparative Biochemistry and Physiology - Part C: Toxicology and Pharmacology, 127: 367-378.# [DOI:10.1016/S0742-8413(00)00164-X]
39. Agency for Toxic Substances and Disease Registry., 2007. Interaction profile for chlorpyrifos, lead, mercury, and methylmercury. Atlanta, GA: Agency for Toxic Substances and Disease Registry. http://www.atsdr. cdc.gov/interactionprofiles/IP-11/ip11.pdf. June 14, 2007.#
40. Becker, K.L., 2001. Principles and practice of endocrinology and metabolism. Lippincott Williams and Wilkins. 2477P.#
41. Brown, S.B.; Adams, B.A.; Cyr, D.G.; Eales, J.G., 2004. Contaminant effects on the teleost fish thyroid. Environmental Toxicology and Chemistry, 23: 1680-1701.# [DOI:10.1897/03-242]
42. Blanton, M.L.; Specker, J.L., 2007. The hypothalamic–pituitary–thyroid (HPT) axis in fish and its role in fish development and reproduction. Critical Reviews in Toxicology, 37: 97-115.# [DOI:10.1080/10408440601123529]
43. Cizdziel, J.; Hinners, T.; Cross, C.; Pollard, J., 2003. Distribution of mercury in the tissues of five species of fresh water fish from Lake Mead, USA. Journal of Environmental Monitoring, 5: 802-807.# [DOI:10.1039/b307641p]
44. Deane, E.E.; Li, J.; Woo, N.Y.S., 2001. Hormonal status and phagocytic activity in sea bream infected with vibriosis. Comparative Biochemistry and Physiology, 129: 687-693.# [DOI:10.1016/S1096-4959(01)00369-4]
45. Devlin, E.W., 2006. Acute toxicity, uptake and histopathology of aqueous methyl mercury to fathead minnow embryos. Ecotoxicology and Environmental Safety, 15: 97–110.# [DOI:10.1007/s10646-005-0051-3]
46. Di Giulio, R.T.; Hinton, D.E., 2008. The Toxicology of Fishes. New York: Taylor & Francis, 1101P.# [DOI:10.1201/9780203647295]
47. Eales, J.G.; Brown, S.B., 2005. Thyroid hormones. In Biochemistry and molecular biology of fishes. Environmental Toxicology, 6: 397-412.#
48. Evans, G.O., 2009. Animal Hematotoxicology. CRC Press, 204P.#
49. Funes, V.; Asensio, E.; Ponce, M.; Infante, C.; Canavate, J.P.; Manchado, M., 2006. Insulin-like growth factors I and II in sole Solea senegalensis: cDNA cloning and quantitation of gene expression in tissues and during larval development. General and Comparative Endocrinology, 149: 166-172.# [DOI:10.1016/j.ygcen.2006.05.017]
50. Fort, D.J.; Degitz, S.; Tietge, J.; Touart, L.W., 2007. The hypothalamic–pituitary–thyroid (HPT) axis in frogs and its role in frog development and reproduction. Critical Reviews in Toxicology, 37: 117-161.# [DOI:10.1080/10408440601123545]
51. Frias-Espericueta, M.G.; Castro-Longoria, R.; Barrón-Gallardo, G.J.; Osuna-López, J.I.; Abad-Rosales, S.M.; Páez-Osuna, F.; Voltolina, D., 2008. Histological changes and survival of Litopenaeus vannamei juveniles with different copper concentrations. Aquaculture, 278: 97-100.# [DOI:10.1016/j.aquaculture.2008.03.008]
52. Goodwin, G.M., 2003. Evidence-based guidelines for treating bipolar disorder: recommendations from the British Association for Psychopharmacology. Journal of Psychopharmacology, 17: 149-173.# [DOI:10.1177/0269881103017002003]
53. Gilbertson, M.; Carpenter, D.O., 2004. An ecosystem approach to the health effects of mercury in the Great Lakes basin ecosystem. Environmental Research, 95: 240-246.# [DOI:10.1016/j.envres.2004.02.015]
54. Jugan, M.L.; Levi, Y.; Blondeau, J.P., 2010. Endocrine disruptors and thyroid hormone physiology. Biochemical Pharmacology, 79: 939-947.# [DOI:10.1016/j.bcp.2009.11.006]
55. Labonne, M.; Othman, D.B.; Luck, J.M., 2001. Lead isotopes in muscels as tracers of metal sources and water movements in a Lagoon (Thau Basin, S. France). Chemical Geology, 181: 181-191.# [DOI:10.1016/S0009-2541(01)00281-9]
56. Lawrence, A.; Hemingway, K., 2003. Effects of pollution on fish, molecular effects and population responses. Blackwell Science Ltd, 362. # [DOI:10.1002/9780470999691]
57. Li, W.; Zha, J.M.; Li, Z.L.; Yang, L.H.; Wang, Z.J., 2009. Effects of exposure to acetochlor on the expression of thyroid hormone related genes in larval and adult rare minnow (Gobiocypris rarus). Aquatic Toxicology, 94: 87-93.# [DOI:10.1016/j.aquatox.2009.06.002]
58. Li, Z.H.; Chen, L.; Wu, Y.H.; Li, P.; Li, Y.F.; Ni, Z.H., 2014. Effects of waterborne cadmium on thyroid hormone levels and related gene expression in Chinese rare minnow larvae. Comparative Biochemistry and Physiology, Part C 161: 53-57.# [DOI:10.1016/j.cbpc.2014.02.001]
59. Martin-Diaz, M.L.; Villena-Lincoln, A.; Bamber, S.; Blasco, J.; DelValls, T.A., 2005. An integrated approach using bioaccumulation and biomarker measurements in female shore crab, Carcinus maenas. Chemospher, 58: 615-626.# [DOI:10.1016/j.chemosphere.2004.08.072]
60. Mommsen, T.P.; Moon, T.W., 2005. Environmental toxicology-biochemistry and molecular biology of fishes. Elsevier Science Ltd, 577P.#
61. Nielsen, J.B.; Hultman, P., 2002. Mercury-induced autoimmunity in mice. Environmental Health Perspectives, 110: 877-881.# [DOI:10.1289/ehp.02110s5877]
62. Okimoto, D.; Tagawa, M.; Koide, Y.; Grau, E.; Hirano, T., 1991. Effects of various adenohypophysial hormones of chum salmon on thyroxine release in vitro in the medaka, Oryzias latipes. Zoological Science, 8: 567-573.#
63. Pratima, G.; Chaurasia, S.S.; Anand, K.; Maiti, P.K.; Gupta, P.; Kar, A., 1997. Influence of cadmium on thyroid hormone concentrations and lipid peroxidation in a fresh water fish, Clarias batrachus. Fresenius Environmental Bulletin, 6: 355-358.#
64. Ricard, A.C.; Daniel, C.; Anderson, P.; Hontela, A., 1998. Effects of subchronic exposure to cadmium chloride on endocrine and metabolic functions in Rainbow Trout Oncorhynchus mykiss. Environmental Contamination Toxicology, 34: 377-381.# [DOI:10.1007/s002449900333]
65. Risso-de Faverney, C.; Devaux, A.; Lafaurie, M.; Girard, J.P.; Bailly, B.; Rahmani, R., 2001. Cadmium induces apoptosis and genotoxicity in rainbow trout hepatocytes through generation of reactive oxygen species. Aquatic Toxicology, 53: 65-76.# [DOI:10.1016/S0166-445X(00)00154-5]
66. Snyder, E.M.; Snyder, S.A.; Kelly, K.L.; Gross, T.S.; Villeneuve, D.L.; Fitzgerald, S.D.; Villalobos, S.A.; Giesy, J.P., 2004. Reproductive responses of common carp (Cyprinus carpio) exposed in cages to influent of the Las Vegas Wash in Lake Mead, Nevada, from late winter to early spring. Environmental Science and Technology, 38: 6385-6395.# [DOI:10.1021/es049690n]
67. Sutton, D.J.; Tchounwou, P.B., 2006. Mercury-induced externalization of phosphatidylserine and caspase 3 activation in human liver carcinoma (HepG2) cells. International Journal of Environmental Research and Public Health, 3(1): 38-42.# [DOI:10.3390/ijerph2006030005]
68. Thangavel, P.; Sumathiral, K.; Karthikeyan, S.; Ramaswamy, M., 2005. Endocrine response of the freshwater teleost, Sarotherodon mossambicus (Peters) to dimecron exposure. Chemosphere, 61: 1083-92.# [DOI:10.1016/j.chemosphere.2005.03.045]
69. Van der Oost, R.; Beyer, J.; Vermeulen, N.P.E., 2003. Fish bioaccumulation and biomarkers in environmental risk assessment: a review. Environmental Toxicology and Pharmacology, 13: 57-149.# [DOI:10.1016/S1382-6689(02)00126-6]
70. Wang, Q.W.; Liang, K.; Liu, J.F.; Yang, L.H.; Guo, Y.Y.; Liu, C.S.; Zhou, B.S., 2013. Exposure of zebrafish embryos/larvae to TDCPP alters concentrations of thyroid hormones and transcriptions of genes involved in the hypothalamic-pituitary-thyroid axis. Aquatic Toxicology, 126: 207-213.# [DOI:10.1016/j.aquatox.2012.11.009]
Add your comments about this article
Your username or Email:

CAPTCHA code



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Safahieh A, Nasrolahzadeh R, Negintaji A. Change of Thyroid Hormone Levels in Mesopotamichthys sharpeyi Exposed to Sub Lethal Concentrations of Cadmium . joc. 2018; 8 (32) :1-8
URL: http://joc.inio.ac.ir/article-1-1207-en.html


Volume 8, Issue 32 (winter 2018) Back to browse issues page
نشریه علمی پژوهشی اقیانوس شناسی Journal of Oceanography
Persian site map - English site map - Created in 0.08 seconds with 30 queries by YEKTAWEB 3727